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NIHR Signal A fifth of people, who have no improvement on antidepressants at four weeks, respond if given more time
An adult with acute depression not yet responding to an antidepressant drug has a 1 in 5 chance of substantial symptom reduction between 5 and 8 weeks if they continue taking it. In those unresponsive after eight weeks, 1 in 10 will respond between 9 and 12 weeks. Changing treatment plans too early can mean needlessly discarding first choice anti-depressants. This is the first systematic review to calculate the proportions of people with a delayed but positive response at different time points....
NIHR Signal Online parental training may help to improve behaviour in children
Online parental training led to reasonable improvements in behaviour problems in children and young people, compared to no training. The findings of this review suggest that additional support and contact – such as “check-in” calls and on-line forums – can help to increase participation. Online training had similar outcomes to face-to-face training. The review identified 14 studies of online training and tested ten different ways of training parents. One large programme ...
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