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NIHR Signal Pain on injection of a widely used anaesthetic may be reduced if a common anti-sickness drug is given first
This review found that giving an anti-sickness drug, like ondansetron, before propofol, an anaesthetic, helped reduce the frequency and severity of injection pain. The intravenous anaesthetic propofol is used at the start of almost all general anaesthetics in the UK but it does often cause unpleasant pain when it is injected. This review of trials looked for trials of any drug in the group of commonly-used anti-sickness drugs called 5HT3 receptor antagonists. Ondansetron, one of these drugs, i...
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