The latest important research, summarised

Staying on antidepressants may prevent a relapse of anxiety

NIHR Signal Staying on antidepressants may prevent a relapse of anxiety

People with anxiety disorders who continued taking antidepressants after successful treatment were less likely to experience a relapse, and relapsed later, than people who stopped taking antidepressants. About 16% of people had a relapse if they remained on antidepressants for on average 44 weeks compared with 36% who stopped after 20 weeks.

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  • 17 January 2018
  • Signal

Single urine samples are just as good as 24-hour collections for diagnosing pre-eclampsia

NIHR Signal Single urine samples are just as good as 24-hour collections for diagnosing pre-eclampsia

The urine spot albumin-creatinine ratio (which is done on a single, on-the-spot sample) reliably identified 99% of pregnant women with high blood pressure who went on to develop severe pre-eclampsia. The spot protein-creatinine ratio, as currently recommended by NICE, was slightly less sensitive identifying over 90% of women. Both spot tests were... Read More

  • 17 January 2018
  • Signal

National tobacco control policies linked to improvements in children’s health

NIHR Signal National tobacco control policies linked to improvements in children’s health

National smoke-free legislation in advanced economies is linked to reduced rates of preterm birth, asthma hospitalisations and serious throat and chest infections in children. Comprehensive smoke-free policies appear to be more effective than policies with only partial or selective introduction.

Smoking increases health risks for the smoker and ... Read More

  • 17 January 2018
  • Signal

Blood test reduces mortality and shortens antibiotic use among adults with chest infection

NIHR Signal Blood test reduces mortality and shortens antibiotic use among adults with chest infection

It may be feasible to use procalcitonin blood levels to guide antibiotic treatment for adults in hospital with a suspected chest infection. By measuring procalcitonin, an indicator of bacterial infection, clinicians could review their diagnosis earlier.

This reduced antibiotic exposure by 2.5 days with fewer adverse effects and also less... Read More

  • 16 January 2018
  • Signal

What works to support residents’ health in care homes and why

NIHR Signal What works to support residents’ health in care homes and why

Long-term relationships and joint working between community health practitioners and care homes are the keys to improving appropriate hospital admissions and access to medications. Additional payments for GPs, jointly agreed protocols, clear role specifications and structured systems have impact only if they trigger and sustain collaborative... Read More

  • 16 January 2018
  • Signal

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