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Repetitive task training can help recovery after stroke

NIHR Signal Repetitive task training can help recovery after stroke

Following a stroke, people who received repetitive task training showed greater improvements in performing functional tasks, such as picking up a cup, standing up and walking. These improvements were sustained for up to six months.

Disability following stroke is common, affecting around half of all stroke survivors. This NIHR-funded review of... Read More

  • 25 April 2017
  • Signal

NIHR Signal Giving immediate antibiotics reduces deaths from sepsis

Giving immediate antibiotics (defined as within one hour) when people present to emergency departments with suspected sepsis reduces their risk of dying by a third compared with later administration.

This meta-analysis of observational data from 23,596 people in emergency department settings confirmed that giving antibiotics within one hour was ... Read More

  • 18 April 2017
  • Signal

New casting technique is an option for older people with ankle fracture

NIHR Signal New casting technique is an option for older people with ankle fracture

A new casting technique called “close contact casting” is an alternative to surgery for older people with ankle fracture. Ankle function at six months was similar in people who had casting and those who had surgery but there are some disadvantages to both that patients and surgeons could consider.

This UK-based NIHR trial recruited... Read More

  • 18 April 2017
  • Signal

Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk

NIHR Signal Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk

Providing very-low-birthweight babies with fortified human donor breast milk made no difference to their developmental neurological outcomes at 18 months compared with giving formula.

This randomised controlled trial looked at 363 babies with birth weights of less than 1500g in neonatal intensive care units in Canada. When the mother’s... Read More

  • 18 April 2017
  • Signal

NIHR Signal Thrombolysis may reduce complications of deep vein thrombosis

Blood clots are cleared quickly for people who develop them in the deep leg veins if they receive thrombolysis drugs alongside other treatments directly into their veins. The chance of successful break down of the clot was compared with the chance following standard anti-clotting drugs alone, such as heparin and warfarin.

This Cochrane review... Read More

  • 18 April 2017
  • Signal

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