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Latest important health research summarised


NIHR Signal Surgery to fix the womb in position after prolapse is an alternative to hysterectomy

Women who have surgery that uses stitches to lift and keep their prolapsed womb in place (called hysteropexy) are less likely to have recurrent symptoms after five years than those who have their womb removed (vaginal hysterectomy).

These results from a Dutch trial involving 204 women showed comparable outcomes for the two surgical options ... Read More

  • 19 February 2020
  • Signal

Intensive Care

NIHR Signal ICU admission decision support tool showed promise but was rarely used

A decision support tool developed to help doctors determine whether patients should be admitted to intensive care showed promise in facilitating patient-clinician communication, but was not often used by doctors, with fewer than 30% using the forms.

Intensive care can deliver lifesaving treatment. It can be invasive and distressing with no... Read More

  • 19 February 2020
  • Signal

Blood transfusion

NIHR Signal Age of stored blood used for transfusions in critically ill children doesn’t affect outcomes

Using more recently-collected red blood cells for transfusions does not reduce organ dysfunction, infection or risk of death in critically ill children, compared with blood that has been stored for longer.

This large, international trial included more than 1,500 children in paediatric intensive care units.

The study provides robust evidence... Read More

  • 19 February 2020
  • Signal


NIHR Signal NHS health check attendance improves with changes to the invitation letter

Invitation letters improve uptake when they address common concerns and reasons for not attending the free NHS Health Checks. People are invited to attend a check every five years between 40 and 74 years, but uptake has been low.

This trial of 6,313 patients from six general practices in Northampton found that presenting reasons for... Read More

  • 19 February 2020
  • Signal

NIHR Themed Review Better health and care for all

This review brings together NIHR-funded research for and about health and social care services for people with learning disabilities. Work is needed to improve care for these people, who experience poorer health and die earlier than the general population. Many of these deaths could be prevented by public health interventions or better access to hi... Read More
  • 13 February 2020
  • Themed Review

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