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Latest important health research summarised

Low emission zone sign

NIHR Signal London’s Low Emission Zone has not been shown to improve children’s respiratory health

The Low Emission Zone covering much of Greater London was introduced between 2008 and 2012 to improve air quality. Some measures of air pollution have slightly reduced over that time, but measures of children’s respiratory health and lung development have not significantly improved.

This NIHR funded study assessed over 2,000 primary... Read More

  • 19 February 2019
  • Signal

Man with sprained ankle

NIHR Signal A new tool helps predict recovery from ankle sprain

The SPRAINED model may improve prediction of people who are at risk of delayed recovery from ankle sprain. This model was developed in the UK using clinical information from 584 adults with ankle injuries.

The model was validated using observational data from 682 people with ankle sprains across 10 different UK emergency departments. Delayed... Read More

  • 19 February 2019
  • Signal

Pot of honey with honey dipper

NIHR Signal Honey may help painful mouth inflammation caused by cancer treatments

Compared to usual care, honey was more likely to reduce moderate or severe pain for patients after radiotherapy and/or chemotherapy treatment.

This systematic review looked at trials from around the world comparing different types of honey with other treatments such as chamomile, golden syrup or placebo. The main outcome was the onset of... Read More

  • 19 February 2019
  • Signal

Omega 6 fatty acids such as pumpkin seeds, sunflower seeds, etc

NIHR Signal A high omega-6 fatty acid diet is unlikely to prevent cardiovascular disease or deaths

Diets or supplements that aim to increase omega-6 fatty acids have no clear effect on the risk of cardiovascular events like heart attacks or stroke, overall deaths or deaths from cardiovascular disease. Omega-6 fatty acids are poly-unsaturated oils largely derived from seeds and nuts such as sunflower oil, corn oil, soybean oil, walnuts and... Read More

  • 19 February 2019
  • Signal

educating patient about weight loss

NIHR Signal No additional weight-loss reported from a lifestyle programme for people with psychosis

For adults with psychosis, such as schizophrenia, who are taking antipsychotic medication, a carefully designed 12-month group diet and exercise programme did not lead to clinically important weight loss after 12 months. The programme was compared with those receiving usual care including written lifestyle advice. Intervention and usual care... Read More

  • 12 February 2019
  • Signal

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