NIHR DC Discover

Latest important health research summarised

NIHR Signal Alternative sedative reduces the risk of acute kidney injury following cardiac surgery

The sedative drug dexmedetomidine can reduce the risk of acute kidney injury when given during non-emergency cardiac surgery. Trial participants who received dexmedetomidine were a third less likely to develop acute kidney injury than those receiving placebo or other treatments. There was no difference in mortality or length of hospital stay.

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  • 10 July 2018
  • Signal

NIHR Signal Nurse staffing levels linked to reports of missed care in adult wards

Nurses are more likely to report omitting necessary care in acute inpatient wards when registered nurse staffing levels are low, even if there are additional healthcare assistants. Care categorised as planning and communication is reported as missed more often than clinical care.

NHS hospitals are responsible for ensuring that the number and... Read More

  • 10 July 2018
  • Signal

NIHR Signal Self-monitoring improves control of high blood pressure compared with GP monitoring alone

Allowing patients who have inadequately controlled high blood pressure to monitor their own blood pressure at home helps their GPs to optimise their management. Patients who self-monitor and visit or talk to their GP when needed for medication adjustments achieve 4mmHg lower systolic blood pressure over 12 months compared with those relying only... Read More

  • 10 July 2018
  • Signal

NIHR Signal One week of steroids may be as effective as two weeks in managing severe COPD

A shorter course of steroids lasting 3 to 7 days appears as effective as the recommended 7 to 14-day standard treatment for managing a flare-up of severe chronic obstructive pulmonary disease.

This update to an earlier Cochrane review looked at randomised clinical trials comparing a short course (7 days or fewer) with a longer course (7 to 14... Read More

  • 10 July 2018
  • Signal

NIHR Themed Review Moving Forward - Physiotherapy for musculoskeletal health and wellbeing

Muskuloskeletal problems are the leading cause of pain and disability in the UK. Characterised by pain and loss of function, these conditions can diminish quality of life, impact on family and social relationships, make everyday activities difficult and limit a person’s capacity to work. Physiotherapy is important for preventing and reducing the ne... Read More
  • 9 July 2018
  • Themed Review

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