Lowering the drink-drive blood alcohol limit in Scotland was not followed by reduced road traffic accidents, perhaps because of a lack of enforcement. While there was a 0.7% reduction in alcohol bought in pubs and restaurants after the new legislation (on-trade sales), there was no significant change in sales of alcohol from shops or supermarkets... Read More
In adults after major trauma who cannot safely be given anti-clotting drugs, placing a removable metal filter in a major vein to the heart (the inferior vena cava) within 3 days of admission does not reduce their chances of having a clot in their lungs (pulmonary embolus) within 90 days, compared with having no filter. The filters do not affect... Read More
For children with a first presentation of nephrotic syndrome, an extended sixteen-week treatment regimen with prednisolone does not reduce the risk of relapse compared with the standard eight-week course. Most children will experience a relapse with either regimen, but the longer course may delay it by a month or so which may, in turn, reduce the... Read More
People who receive exercise training following surgery for lung cancer can walk about 57 metres further in six minutes than controls who did not exercise. After surgery like this to remove all or part of a lung, people typically manage about 500 metres in six minutes on the test, and anything above 20 metres is considered a worthwhile... Read More
Quadruple drug therapy for people starting HIV treatment offers no benefit over the currently recommended triple therapy.
Antiretroviral (anti-HIV) therapy is highly effective, with almost all treated individuals in the UK surviving as long as non-infected people. The courses now available mean those treated are usually unable to pass on the... Read More